Extended Submission deadline: 7 November 2023

Seize the opportunity to be at the forefront of a revolution in short-read sequencing's accuracy with PacBio Onso system. Equipped with cutting-edge technology using state-of-the-art sequencing by binding (SBB) chemistry , Onso is set to redefine the landscape of short-read sequencing. Take your research to new heights by participating in this Asia-Pacific exclusive Onso SBB Grant.


15× higher accuracy than SBS sequencers

SBB chemistry delivers extraordinary levels of accuracy and sensitivity to confidently identify rare variants missed by other short-read sequencing platforms.

Less sequencing required

At Q30, the amount of coverage needed for certain applications (e.g. liquid biopsy research) is not economically feasible. The Onso system’s Q40+ performance provides high quality results at up to four fold less read depth than SBS.

Power through difficult to sequence regions of the genome

Near-perfect sequencing provides researchers accurate characterization of low complexity, highly repetitive regions for achieving more error-free genomes.

Seamless integration with existing short-read sequencing ecosystems

The Onso system will be available with an accuracy-enhanced library prep solution that enables a diverse set of popular short-read applications. Plus, third-party sample and library prep solutions are supported on Onso through a simple library conversion process. The Onso FASTQ file output ensures compatibility with downstream secondary and tertiary short-read analysis tools.


Sequencing by binding (SBB) is an innovative sequencing technology that delivers exceptional NGS accuracy. By incorporating native nucleotides and removing the need to cleave fluorescent modifications, the sequencing strand has minimal scarring and results in higher accuracy base calls than other sequencing chemistries.


Learn more about Onso and SBB technology to prepare for your proposal.

Submission Closed. We are currently reviewing applicants and will notify you via email.

How to apply for this Onso SBB Grant – the A-T-C-Gs

Get to know the A-T-C-Gs of this PacBio Onso SBB Grant

Act fast – This Onso SBB Grant is only open for a short time, so there is no time to wait. The deadline for submitting your proposal titles is 7 November 2023 at 23:59 (Singapore Time).
Tell us about your research – Projects large and small will be considered, with the possibility of multiple winners across human genomics, microbial genomics, cancer research and plant and animal genomics. Onso flow cells and associated library preps are up for grabs.
Connect and inspire – We encourage scientists of all career stages to apply, so share this opportunity with your colleagues and win sequencing on the first Onso unit in APAC with the option of data analysis.
Get in touch – We are here to answer your questions about this SBB Chemistry Experience or the official rules.