WEBINAR
Accurate fusion gene detection is critical in cancer research, as fusion genes can serve as biomarkers or therapeutic targets. Short reads can identify fusion gene breakpoints but cannot offer isoform-resolution fusion discovery, which limits their utility. In contrast, long-read RNA sequencing using the PacBio Kinnex full-length RNA and single-cell RNA kits can offer full-length isoform information in bulk and single-cell RNA samples.
In this webinar, you will learn about CTAT-LR-fusion, a new bioinformatics tool for detecting known and novel fusion transcripts from PacBio long-read isoform sequencing data, with applications to bulk and single-cell tumor transcriptomes. Get an in-depth comparison of this innovative tool against other existing long-read fusion detection methods on simulated data, reference cancer cell lines, and patient-derived tumor samples, demonstrating its superior performance.
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Don’t forget to stick around and have your questions answered during a live Q&A session with the webinar speakers!
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Elizabeth Tseng, PhD
Associate Director, Product Marketing, PacBio
Brian Haas, PhD
Principal Computational Scientist, Methods Development Laboratory, Broad Clinical Labs, Broad Institute of MIT and Harvard