Decoding Cancer with Near–Single-Cell Spatial Isoforms and Immune Receptor Profiling

Understanding tumor progression and immune response requires resolving transcriptomic complexity directly within intact tissue. In this webinar, learn how long-read sequencing combined with near-single-cell spatial transcriptomics uncovers isoform-level heterogeneity and precisely localizes immune receptor clonotypes within their native tissue context.

Two expert speakers will show how integrating long-read sequencing with emerging spatial technologies delivers deeper biological insight than short-read approaches. See examples from solid tumor transcriptomics in breast and colon cancer, as well as high-resolution immune receptor profiling using the 10x Genomics Visium HD platform.

Register to:

Discover how spatial profiling provides a more complete and biologically meaningful view of tumor–immune interactions.
Learn how HiFi sequencing enables near-single-cell resolution spatial transcriptomics.
Understand how precise localization of paired BCR and TCR clonotypes reduces spatial mixing and improves immune cell assignment.

A live Q&A session will follow the presentations, with opportunities to have your questions answered by the speakers.

SPEAKERS

Elizabeth Tseng, PhD

Associate Director, Product Marketing
PacBio
Host + moderator

Lieke Michielsen

Postdoctoral Associate
Brain and Mind Research Institute
Weill Cornell Medicine

Patrick Truong

Postdoctoral Associate
Department of Gene Technology
KTH Royal Institute of Technology
Science for Life Laboratory, Sweden