Long-read RNA sequencing reveals a regulatory role for splicing in immunotherapy responses

Now open for a limited time: get a closer look at splicing in immunotherapy response

PacBio is re-opening this popular session for researchers interested in cancer transcriptomics, RNA isoform discovery, and immunotherapy response.

Hear Olga Anczukow, PhD and Ryan Englander discuss how PacBio Iso-Seq long-read RNA sequencing helped examine transcriptome splicing in lung cancer research, including novel mRNA isoforms that may influence immune responsiveness.

The session gives researchers a practical look at how full-length RNA sequencing can uncover transcript structure, isoform diversity, and splicing events that may add important context beyond gene-level expression.

What you'll get:

✔ A focused look at how transcriptome splicing may affect immune function in lung cancer research
✔ Expert perspective on using PacBio Iso-Seq sequencing to examine full-length RNA isoforms
✔ Insight into a potentially regulatory and predictive role for immunotherapy outcomes for the STAT2 gene

Browse the speaker details below, and register to access the complete session while it is available.

What you'll get:

A clear introduction to HiFi sequencing and its role in clinical laboratory workflows
Expert perspectives on evaluating, validating, and implementing HiFi sequencing
Insight into where HiFi WGS and PureTarget may support rare disease and carrier screening workflows
A practical look at assay consolidation through a single HiFi sequencing workflow
Considerations for teams planning for workflow fit, adoption, and scale

FEATURED SESSION SPEAKERS