Accelerate time-critical genomic research with rapid HiFi whole genome sequencing.
Fill out the form now to access your complimentary Rapid HiFi WGS Resource Bundle.
Rapid whole genome sequencing (rWGS) transforms time-critical rare disease and neonatal genomic research for researchers and clinicians studying urgent cases. In places like neonatal intensive care units (NICU), accelerated rWGS workflows can potentially shorten turnaround times and provide a more complete view of the genome in a single assay.
The PacBio rapid HiFi WGS workflow combines optimized DNA extraction, streamlined library preparation, accelerated sequencing, and GPU-enabled analysis to generate genome-wide variant calls in under 30 hours from DNA extraction to VCF generation. HiFi sequencing is able to capture complex variant classes such as structural variants, repeat expansions, phased haplotypes, and difficult-to-sequence genomic regions that may be challenging to resolve with conventional approaches.
Complete the form for instant access to:
✔ Blog article (PDF) introducing the rapid HiFi WGS workflow and its applications for time-critical genomic research
✔ Technical note detailing the rapid HiFi WGS workflow, performance metrics, and implementation considerations
✔ ESHG scientific poster highlighting validation data across different sample types and comprehensive variant detection using the rapid workflow
✔ Application note describing the PacBio WGS analysis workflow and rapid variant calling pipeline
Interested in implementing the rapid workflow? The latest Rapid HiFi WGS protocol is available upon request through your PacBio representative.