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In clinical and translational research, focusing on the genes, variants, and regions most relevant to your study can improve both efficiency and insight. However, many current workflows rely on multiple sequential or reflex tests, which increase time, cost, and complexity while still leaving some questions unanswered.
PacBio HiFi long-read sequencing changes this by delivering high accuracy, long-read information in a single platform. Whether your targets involve complex genes, structural variants, repeat expansions, or phasing requirements, HiFi sequencing provides the depth and context needed to generate confident results from the start.
HiFi sequencing supports flexible, high-confidence targeted resequencing through three complementary strategies:
✔ Long-range PCR amplicon sequencing
✔ CRISPR-Cas9 PCR-free enrichment with PureTarget
✔ Hybrid capture
Each approach is designed to help you focus on the regions that matter most while reducing the need for multiple assays. By consolidating what traditionally requires several tests into one streamlined workflow, HiFi sequencing helps minimize time to insight, lower overall testing costs, and deliver more comprehensive answers earlier in the research process.
Unlock expert resources to optimize your targeted sequencing strategy. Explore how one comprehensive long-read platform can replace multiple tests, reduce complexity, and provide first-pass answers with confidence.